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Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.

Human immunology - 1 Mar 2024

Halimi Hossein, Mirzazadeh Sara, Kalantar Kurosh, Hajimaghsoodi Maryam, Ramzi Mani, Farjadian Shirin

Abstract excerpt

B-cell acute lymphoblastic leukemia (B-ALL), the most predominant type of ALL, is less common and incurable among adults. Regarding the pivotal role of NK cells in immune surveillance against hematological malignancies, studying the effective factors in regulating their function, particularly KIRs as the most important NK cell receptors and HLA-I molecules as their main ligands, is of importance. Since NK...

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Identifiers

PMID: 38262874
DOI: 10.1016/j.humimm.2024.110750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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