Article
Association of SERPINE2 gene with the risk of chronic obstructive pulmonary disease and spirometric phenotypes in northern Han Chinese population.
Molecular biology reports - 1 Feb 2012
An Li, Yang Ting, Zhang Yongbiao, Lin Yingxiang, Zhang Hong, Jiao Xia, Hua Lin, Dai Huaping, Wang Chen
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by multiple genes and environmental factors. The SERPINE2 gene has recently been demonstrated to be associated with COPD onset in a non-East Asian population. In this study, we genotyped 20 single nucleotide polymorphisms (SNPs) in SERPINE2 from 310 cases and 203 controls, all of which belong to the Han from North China. Genotype...
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