Article
SERPINE2 polymorphisms and chronic obstructive pulmonary disease.
Journal of Korean medical science - 1 Dec 2009
Cha Seung Ick, Kang Hyo-Gyoung, Choi Jin Eun, Kim Min Jung, Park Jaeho, Lee Won Kee, Kim Chang Ho, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
A number of genome-wide linkage analyses have identified the 2q33.3-2q37.2 region as most likely to contain the genes that contribute to the susceptibility to chronic obstructive pulmonary disease (COPD). It was hypothesized that the SERPINE2 gene, which is one of the genes located at the 2q33.3-2q37.2 region, may act as a low-penetrance susceptibility gene for COPD. To test this hypothesis, the association of...
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