Article
SERPINE2 haplotype as a risk factor for panlobular type of emphysema.
BMC medical genetics - 7 Dec 2011
Kukkonen Mari K, Tiili Emmi, Hämäläinen Satu, Vehmas Tapio, Oksa Panu, Piirilä Päivi, Hirvonen Ari
Abstract excerpt
BACKGROUND: SERPINE2 (serpin peptidase inhibitor, clade E, member 2) has previously been identified as a positional candidate gene for chronic obstructive pulmonary disease (COPD) and has subsequently been associated to COPD and emphysema in several populations. We aimed to further examine the role of SERPINE2 polymorphisms in the development of pulmonary emphysema and different emphysema subtypes. METHODS: Four...
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