Article
RAS gene mutations and histomorphometric measurements in oral squamous cell carcinoma.
Biotechnic & histochemistry : official publication of the Biological Stain Commission - 1 Nov 2023
Mustansar Tazeen, Mirza Talat, Hussain Mushtaq
Abstract excerpt
Members of the RAS gene family frequently are mutated in cancers including oral squamous cell carcinoma (OSCC). We investigated the correlation of histological characteristics of OSCC with RAS gene mutations. We graded tumors and extracted genomic DNA from OSCC. The first two exons of KRAS, HRAS and NRAS genes were subjected to PCR amplification and DNA sequencing followed by bioinformatic analysis to explore the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
