SNCA variants are associated with increased risk for multiple system atrophy.

doi:10.1002/ana.21685

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

SNCA variants are associated with increased risk for multiple system atrophy.

Annals of neurology - 1 May 2009

Scholz Sonja W, Houlden Henry, Schulte Claudia, Sharma Manu, Li Abi, Berg Daniela, Melchers Anna, Paudel Reema, Gibbs J Raphael, Simon-Sanchez Javier, Paisan-Ruiz Coro, Bras Jose, Ding Jinhui, Chen Honglei, Traynor Bryan J, Arepalli Sampath, Zonozi Ryan R, Revesz Tamas, Holton Janice, Wood Nick, Lees Andrew, Oertel Wolfgang, Wüllner Ullrich, Goldwurm Stefano, Pellecchia Maria Teresa, Illig Thomas, Riess Olaf, Fernandez Hubert H, Rodriguez Ramon L, Okun Michael S, Poewe Werner, Wenning Gregor K, Hardy John A, Singleton Andrew B, Del Sorbo Francesca, Schneider Susanne, Bhatia Kailash P, Gasser Thomas

Abstract excerpt

To test whether the synucleinopathies Parkinson's disease and multiple system atrophy (MSA) share a common genetic etiology, we performed a candidate single nucleotide polymorphism (SNP) association study of the 384 most associated SNPs in a genome-wide association study of Parkinson's disease in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Multiple System Atrophy

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Risk

Source

Open in PubMed Open full text

Identifiers

PMID: 19475667
DOI: 10.1002/ana.21685
PMCID: PMC3520128

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19475667-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNCA variants are associated with increased risk for multiple system atrophy.PMID 19475667Read ↗

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.Semantic proximity Read ↗

Genetic Analysis and Literature Review of SNCA Variants in Parkinson's DiseaseSemantic proximity Read ↗

Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study.Semantic proximity Read ↗

Genome sequence analyses identify novel risk loci for multiple system atrophy.Semantic proximity Read ↗

The genetic basis of multiple system atrophySemantic proximity Read ↗

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.Semantic proximity Read ↗

Genetics of Multiple System Atrophy and Progressive Supranuclear Palsy: A Systemized Review of the Literature.Semantic proximity Read ↗

Genetic players in multiple system atrophy: unfolding the nature of the beast.Semantic proximity Read ↗

Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease.Semantic proximity Read ↗

Genetic variability in SNCA and Parkinson's disease.Semantic proximity Read ↗

A comprehensive analysis of SNCA-related genetic risk in sporadic parkinson disease.Semantic proximity Read ↗

Update on novel familial forms of Parkinson's disease and multiple system atrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.