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Article

EPLIN is a Negative Regulator of Prostate Cancer Growth and Invasion

23 May 2011

Abstract excerpt

PURPOSE: We investigated the importance of EPLIN, a cytoskeletal associated protein implicated in cancer, in clinical prostate cancer and its role in the PC-3 prostate cancer cell line (ATCC™). MATERIALS AND METHODS: Full-length human EPLIN cDNA was cloned into a pEF6 expression vector and used to transfect the PC-3 human prostate cancer cell line. Cells over expressing EPLIN were termed PC-3(EPLIN EXP) while...

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PMID: 21600601
DOI: 10.1016/j.juro.2011.03.038

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