Article
No evidence for association between SLC11A1 and visceral leishmaniasis in India.
BMC medical genetics - 20 May 2011
Mehrotra Sanjana, Oommen Joyce, Mishra Anshuman, Sudharshan Medhavi, Tiwary Puja, Jamieson Sarra E, Fakiola Michaela, Rani Deepa Selvi, Thangaraj Kumarasamy, Rai Madhukar, Sundar Shyam, Blackwell Jenefer M
Abstract excerpt
BACKGROUND: SLC11A1 has pleiotropic effects on macrophage function and remains a strong candidate for infectious disease susceptibility. 5' and/or 3' polymorphisms have been associated with tuberculosis, leprosy, and visceral leishmaniasis (VL). Most studies undertaken to date were under-powered, and none has been replicated within a population. Association with tuberculosis has replicated variably across...
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