Article
SLC11A1 polymorphisms and host susceptibility to cutaneous leishmaniasis in Pakistan.
Parasites & vectors - 7 Jan 2017
Sophie Mariam, Hameed Abdul, Muneer Akhtar, Samdani Azam J, Saleem Saima, Azhar Abid
Abstract excerpt
BACKGROUND: The vector-borne cutaneous leishmaniasis (CL) is endemic in several regions of Pakistan mainly affecting poor populations. Host genetic factors, particularly SLC11A1 (solute carrier transmembrane protein) within macrophages, play a crucial role in disease pathology and susceptibility. Association of SLC11A1 with cutaneous leishmaniasis, a neglected tropical disease, is not well established....
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