Article
Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers.
Blood - 28 Jul 2011
Rockova Veronika, Abbas Saman, Wouters Bas J, Erpelinck Claudia A J, Beverloo H Berna, Delwel Ruud, van Putten Wim L J, Löwenberg Bob, Valk Peter J M
Abstract excerpt
Numerous molecular markers have been recently discovered as potential prognostic factors in acute myeloid leukemia (AML). It has become of critical importance to thoroughly evaluate their interrelationships and relative prognostic importance. Gene expression profiling was conducted in a well-characterized cohort of 439 AML patients (age < 60 years) to determine expression levels of EVI1, WT1, BCL2, ABCB1, BAALC,...
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