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Article

A targeted next-generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice.

Cancer medicine - 1 Feb 2017

Lin Po-Han, Li Huei-Ying, Fan Sheng-Chih, Yuan Tzu-Hang, Chen Ming, Hsu Yu-Hua, Yang Yu-Hsuan, Li Long-Yuan, Yeh Su-Peng, Bai Li-Yuan, Liao Yu-Min, Lin Chen-Yuan, Hsieh Ching-Yun, Lin Ching-Chan, Lin Che-Hung, Lien Ming-Yu, Chen Tzu-Ting, Ni Yen-Hsuan, Chiu Chang-Fang

Abstract excerpt

Conventional cytogenetics can categorize patients with acute myeloid leukemia (AML) into favorable, intermediate, and unfavorable-risk groups; however, patients with intermediate-risk cytogenetics represent the major population with variable outcomes. Because molecular profiling can assist with AML prognosis and next-generation sequencing allows simultaneous sequencing of many target genes, we analyzed 260 genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28070990
DOI: 10.1002/cam4.969
PMCID: PMC5313641

Genes

FLT3
TET2
ASXL1
DNMT3A
IDH2
KIT
NPM1
PHF6
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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