Article
Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jun 2011
Mohamed Jamal A, DuPont Herbert L, Flores Jose, Palur Himaja, Nair Parvathy, Jiang Zhi-Dong, Guo Dongchuan, Belkind-Gerson Jaime, Okhuysen Pablo C
Abstract excerpt
BACKGROUND: Under normal conditions, the expression of CD14, which is the principal receptor for bacterial lipopolysaccharide, is down-regulated in the intestinal mucosa but increases in response to inflammatory stimuli. The aim of the present study was to investigate whether fecal CD14 levels increased in response to infection with diarrheagenic Escherichia coli and whether single nucleotide polymorphisms (SNPs)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.