Article
A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients.
Human immunology - 1 May 2010
Joshita Satoru, Umemura Takeji, Yoshizawa Kaname, Katsuyama Yoshihiko, Tanaka Eiji, Ota Masao
Abstract excerpt
Primary biliary cirrhosis (PBC) is a complex autoimmune liver disease with an etiology that remains to be conclusively elucidated. As such, we screened the human genome for genes that might influence PBC susceptibility or resistance using 400 microsatellite markers. A strong candidate gene indicated by susceptibility microsatellite markers was further evaluated by association analysis using single nucleotide...
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