Article
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity.
RNA biology - 1 Jan 2000
Denison Mark R, Graham Rachel L, Donaldson Eric F, Eckerle Lance D, Baric Ralph S
Abstract excerpt
In order to survive and propagate, RNA viruses must achieve a balance between the capacity for adaptation to new environmental conditions or host cells with the need to maintain an intact and replication competent genome. Several virus families in the order Nidovirales, such as the coronaviruses (CoVs) must achieve these objectives with the largest and most complex replicating RNA genomes known, up to 32 kb of...
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