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Article

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jun 2011

Koide Masahiro, Ikeda Koji, Akakabe Yoshiki, Kitamura Youhei, Ueyama Tomomi, Matoba Satoaki, Yamada Hiroyuki, Okigaki Mitsuhiko, Matsubara Hiroaki

Abstract excerpt

Endothelial and endothelial progenitor cells (ECs and EPCs) play a fundamental role in angiogenesis that is essential for numerous physiological and pathological processes. The phosphatase and tensin homolog (PTEN)/ phosphoinositide 3-kinase (PI3K) pathway has been implicated in angiogenesis, but the mechanism in the regulation of this pathway in ECs and EPCs is poorly understood. Here we show that ARIA...

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Identifiers

PMID: 21593423
DOI: 10.1073/pnas.1101296108
PMCID: PMC3111316

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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