Article
Retardation of retinal vascular development in apelin-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2008
Kasai Atsushi, Shintani Norihito, Kato Hideaki, Matsuda Satoshi, Gomi Fumi, Haba Ryota, Hashimoto Hitoshi, Kakuda Michiya, Tano Yasuo, Baba Akemichi
Abstract excerpt
OBJECTIVE: Apelin is an endogenous ligand for the G protein-coupled receptor, APJ, and participates in multiple physiological processes. To identify the roles of endogenous apelin, we investigated the phenotype of apelin-deficient (apelin-KO) mice. METHODS AND RESULTS: Apelin-KO mice showed impai...
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