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Abnormal iron uptake and liver cancer

15 Sept 2009

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Iron overload represents a significant risk factor in the development of HCC. Hereditary hemochromatosis (HH) is a genetic iron overload disease characterized by hepatic iron accumulation. The potential link between these two conditions leads to significant curiosity about regulation of iron homeostasis. Importantly, one of the HH genes,...

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PMID: 19571663
DOI: 10.4161/cbt.8.18.9146

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