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Article

Zinc is a negative regulator of hepatitis C virus RNA replication

21 Sept 2006

Abstract excerpt

BACKGROUND/AIMS: Hepatitis C virus (HCV) infection is a significant global public health problem. In clinical studies, zinc has been closely related to the pathogenesis of chronic hepatitis C. However, the role of zinc in both viral replication and the expression of viral proteins remains unclear. We aimed to clarify the effect of zinc on the replication of HCV in vitro. METHODS: We incubated subgenomic HCV...

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PMID: 17032412
DOI: 10.1111/j.1478-3231.2006.01352.x

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