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The Cbk1-Ace2 axis guides Candida albicans from yeast to hyphae and back again

12 Jan 2021

Abstract excerpt

Since its description in S. cerevisiae, the Regulation of Ace2 and Morphogenesis (RAM) pathway has been studied for nearly 20 years in multiple model and pathogenic fungi. In pathogenic fungi, the RAM pathway carries out many functions through mechanisms that remain to be defined in detail. Recently, we reported that Cbk1-mediated phosphorylation of the transcription factor Ace2 functions to repress the...

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PMID: 33433733
DOI: 10.1007/s00294-020-01152-1

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