Article
The N-terminal region of the Neurospora NDR kinase COT1 regulates morphology via its interactions with MOB2A/B.
Molecular microbiology - 1 Oct 2013
Ziv Carmit, Feldman Daria, Aharoni-Kats Liran, Chen She, Liu Yi, Yarden Oded
Abstract excerpt
Nuclear Dbf2p-related (NDR) protein kinases are important for cell differentiation and polar morphogenesis in various organisms, yet some of their functions are still elusive. Dysfunction of the Neurospora crassa NDR kinase COT1 leads to cessation of tip extension and hyperbranching. NDR kinases require the physical interaction between the kinase's N-terminal region (NTR) and the MPS1-binding (MOB) proteins for...
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