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Article

The mutation of V79 cells by N-nitrosobis(2-oxopropyl)amine activated by pancreas acinar and duct tissue from Syrian hamsters and MRC-Wistar rats.

Mutation research - 1 Apr 1990

Lawson T, Kolar C, Nagel D

Abstract excerpt

The mutagenicity of N-nitrosobis(2-oxopropyl)amine was measured in the V79 assay using homogenates of acinar cells and duct tissue from the pancreases of Syrian hamsters and MRC-Wistar rats as the activating systems. Mutations at the sodium/potassium ATPase and hypoxanthine:guanine phosphoribosyl...

Topics

Animals
Biotransformation
Cricetinae
Drug Resistance
Hypoxanthine Phosphoribosyltransferase
Male
Mesocricetus
Mutagenicity Tests
Mutation
Nitrosamines
Ouabain
Pancreas

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic Ducts

Rats

Rats, Inbred Strains

Sodium-Potassium-Exchanging ATPase

Thioguanine

Source

Identifiers

PMID: 2158624
DOI: 10.1016/0165-1218(90)90073-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2158624-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The mutation of V79 cells by N-nitrosobis(2-oxopropyl)amine activated by pancreas acinar and duct tissue from Syrian hamsters and MRC-Wistar rats.PMID 2158624Read ↗

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