Article
High alpha-2,6-sialylation of N-acetyllactosamine sequences in ras-transformed rat fibroblasts correlates with high invasive potential.
Glycobiology - 1 Mar 1995
Le Marer N, Stéhelin D
Abstract excerpt
Through cloning experiments with the FRras EJ4 cell line, previously described to exhibit a Sambucus nigra agglutinin (SNA)+ phenotype, three clones with a SNA- phenotype were isolated. All the selected SNA+ and SNA- clones expressed the ras oncoprotein and cloned in soft agar with the same efficiency. We were interested in studying the adhesion and invasion properties of the FRras cells presenting a SNA + or -...
Topics
- Amino Sugars
- Animals
- Carbohydrate Conformation
- Carbohydrate Sequence
- Cell Adhesion
- Cell Aggregation
- Cell Line, Transformed
- Cell Membrane
- Cell Transformation, Neoplastic
- Clone Cells
- Fibroblasts