Frequency and mechanisms of factor independence in IL-3-dependent cell lines.

doi:10.1007/BF01233041

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Article

Frequency and mechanisms of factor independence in IL-3-dependent cell lines.

Somatic cell and molecular genetics - 1 Mar 1990

Isfort R J

Abstract excerpt

Interleukin-3 (IL-3) -dependent cell lines were tested for spontaneous mutation frequency with respect to two markers, growth factor-independent growth and 8-azaguanine-resistant growth. The mutation frequency for the growth factor-independent growth was approximately equal to that of 8-azaguanin...

Topics

Animals
Azaguanine
Cell Line
Chromosome Mapping
DNA Restriction Enzymes
Electrophoresis, Gel, Two-Dimensional
Gene Expression
Gene Frequency
Genetic Markers
Growth Substances
Hypoxanthine Phosphoribosyltransferase
Immunoblotting
Interleukin-3
Leukemia, Myeloid
Mutation
Phenotype
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-myc

Source

Open in PubMed

Identifiers

PMID: 2157296
DOI: 10.1007/BF01233041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2157296-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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