Article
Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1).
The Journal of biological chemistry - 8 Jul 2011
Kamishikiryo Jun, Fukuhara Hideo, Okabe Yuki, Kuroki Kimiko, Maenaka Katsumi
Abstract excerpt
Human Th17 cells express high levels of CD161, a member of the killer cell lectin-like receptor (KLR) family (also referred to as NK receptor-P1A (NKRP1A) or KLRB1), as a representative marker. CD161 is also expressed on natural killer (NK) cells and NKT cells. Lectin-like transcript 1 (LLT1), another KLR family member, was recently identified as a ligand for CD161. This interaction may play pivotal roles in the...
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