Article
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells.
Scandinavian journal of immunology - 1 Jul 2021
Eriksson Anna M, Leikfoss Ingvild Sørum, Abrahamsen Greger, Sundvold Vibeke, Isom Martine Mesel, Keshari Pankaj K, Rognes Torbjørn, Landsverk Ole J B, Bos Steffan D, Harbo Hanne F, Spurkland Anne, Berge Tone
Abstract excerpt
C-type lectin-like domain family 16 member A (CLEC16A) is associated with autoimmune disorders, including multiple sclerosis (MS), but its functional relevance is not completely understood. CLEC16A is expressed in several immune cells, where it affects autophagic processes and receptor expression. Recently, we reported that the risk genotype of an MS-associated single nucleotide polymorphism in CLEC16A intron 19...
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