Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display.

Biochemical and biophysical research communications - 3 Jun 2011

Han Thomas, Sui Jianhua, Bennett Andrew S, Liddington Robert C, Donis Ruben O, Zhu Quan, Marasco Wayne A

Abstract excerpt

Highly pathogenic H5N1 avian influenza viruses pose a debilitating pandemic threat. Thus, understanding mechanisms of antibody-mediated viral inhibition and neutralization escape is critical. Here, a robust yeast display system for fine epitope mapping of viral surface hemagglutinin (HA)-specific antibodies is demonstrated. The full-length H5 subtype HA (HA0) was expressed on the yeast surface in a correctly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Epitope Mapping

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A Virus, H5N1 Subtype

Share to Peptide Library

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 21569761
DOI: 10.1016/j.bbrc.2011.04.139
PMCID: PMC3119598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display.PMID 21569761Read ↗

Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational ScanningSemantic proximity Read ↗

Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast displaySemantic proximity Read ↗

Fine antigenic variation within H5N1 influenza virus hemagglutinin's antigenic sites defined by yeast cell surface display.Semantic proximity Read ↗

Complete mapping of viral escape from neutralizing antibodies.Semantic proximity Read ↗

A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus HemagglutininSemantic proximity Read ↗

In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificitySemantic proximity Read ↗

Epitope Mapping of the Hemagglutinin Molecule of a Highly Pathogenic H5N1 Influenza Virus by Using Monoclonal AntibodiesSemantic proximity Read ↗

Comprehensive Analysis and Characterization of Linear Antigenic Domains on HN Protein from Genotype VII Newcastle Disease Virus Using Yeast Surface Display System.Semantic proximity Read ↗

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies.Semantic proximity Read ↗

Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodiesSemantic proximity Read ↗

Cross-neutralization of influenza A viruses mediated by a single antibody loop.Semantic proximity Read ↗

Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.