Article
Comprehensive Analysis and Characterization of Linear Antigenic Domains on HN Protein from Genotype VII Newcastle Disease Virus Using Yeast Surface Display System.
PloS one - 1 Jan 2015
Li Tao, Wang Gaoling, Shi Bingtian, Liu Peixin, Si Wei, Wang Bin, Jiang Li, Zhou Lunjiang, Xiu Jinsheng, Liu Henggui
Abstract excerpt
Circulation of genotype VII Newcastle disease virus (NDV) has posed a great threat for the poultry industry worldwide. Antibodies against Hemagglutinin-neuraminidase (HN), a membrane protein of NDV with critical roles in NDV infection, have been reported to provide chickens protection from NDV infection. In this study, we comprehensively analyzed the in vivo antibody responses against the linear antigenic domains...
Topics
- Animals
- Antigens, Viral
- Cell Surface Display Techniques
- Chickens
- Epitope Mapping
- Epitopes
- Genotype
- HN Protein
- Immune Sera
- Models, Molecular
- Newcastle Disease