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Article

A hidden two-locus disease association pattern in genome-wide association studies.

BMC bioinformatics - 14 May 2011

Yang Can, Wan Xiang, Yang Qiang, Xue Hong, Tang Nelson L S, Yu Weichuan

Abstract excerpt

BACKGROUND: Recent association analyses in genome-wide association studies (GWAS) mainly focus on single-locus association tests (marginal tests) and two-locus interaction detections. These analysis methods have provided strong evidence of associations between genetics variances and complex diseases. However, there exists a type of association pattern, which often occurs within local regions in the genome and is...

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Identifiers

PMID: 21569557
DOI: 10.1186/1471-2105-12-156
PMCID: PMC3116488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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