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Article

Osteopontin enhances HIV replication and is increased in the brain and cerebrospinal fluid of HIV-infected individuals.

Journal of neurovirology - 1 Aug 2011

Brown Amanda, Islam Tanzeem, Adams Robert, Nerle Sujata, Kamara Masiray, Eger Caitlin, Marder Karen, Cohen Bruce, Schifitto Giovanni, McArthur Justin C, Sacktor Ned, Pardo Carlos A

Abstract excerpt

Despite effective and widely available suppressive anti-HIV therapy, the prevalence of mild neurocognitive dysfunction continues to increase. HIV-associated neurocognitive disorder (HAND) is a multifactorial disease with sustained central nervous system inflammation and immune activation as prominent features. Inflammatory macrophages, HIV-infected and uninfected, play a central role in the development of HIV...

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Identifiers

PMID: 21556958
DOI: 10.1007/s13365-011-0035-4
PMCID: PMC3331788

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SPP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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