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Article

HIV-1 Nef in macrophage-mediated disease pathogenesis.

International reviews of immunology - 1 Dec 2012

Lamers Susanna L, Fogel Gary B, Singer Elyse J, Salemi Marco, Nolan David J, Huysentruyt Leanne C, McGrath Michael S

Abstract excerpt

Combined anti-retroviral therapy (cART) has significantly reduced the number of AIDS-associated illnesses and changed the course of HIV-1 disease in developed countries. Despite the ability of cART to maintain high CD4+ T-cell counts, a number of macrophage-mediated diseases can still occur in HIV-infected subjects. These diseases include lymphoma, metabolic diseases, and HIV-associated neurological disorders....

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Topics

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Share to Disease Progression
Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Host-Pathogen Interactions

Share to Macrophages

Share to nef Gene Products, Human Immunodeficiency Virus

Share to Signal Transduction

Share to Virus Replication

Source

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Identifiers

PMID: 23215766
DOI: 10.3109/08830185.2012.737073
PMCID: PMC3544535

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