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Article

HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels.

Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 2002

Gonzalez Enrique, Rovin Brad H, Sen Luisa, Cooke Glen, Dhanda Rahul, Mummidi Srinivas, Kulkarni Hemant, Bamshad Michael J, Telles Vanessa, Anderson Stephanie A, Walter Elizabeth A, Stephan Kevin T, Deucher Michael, Mangano Andrea, Bologna Rosa, Ahuja Seema S, Dolan Matthew J, Ahuja Sunil K

Abstract excerpt

Studies in humans and in experimental models of HIV-1 infection indicate an important role for monocyte chemoattractant protein-1 (MCP-1; also known as CC chemokine ligand 2), a potent chemoattractant and activator of mononuclear phagocytes (MP) in the pathogenesis of HIV-associated dementia (HAD...

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Identifiers

PMID: 12374865
DOI: 10.1073/pnas.202357499
PMCID: PMC129777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12374865-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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