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Article

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model.

Malaria journal - 10 May 2011

Tipsuwan Wachiraporn, Srichairatanakool Somdet, Kamchonwongpaisan Sumalee, Yuthavong Yongyuth, Uthaipibull Chairat

Abstract excerpt

BACKGROUND: The prevalence of drug resistance amongst the human malaria Plasmodium species has most commonly been associated with genomic mutation within the parasites. This phenomenon necessitates evolutionary predictive studies of possible resistance mutations, which may occur when a new drug is introduced. Therefore, identification of possible new Plasmodium falciparum dihydrofolate reductase (PfDHFR) mutants...

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Source

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Identifiers

PMID: 21554743
DOI: 10.1186/1475-2875-10-119
PMCID: PMC3100258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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