Article
Complex Relationship between Obesity and the Fat Mass and Obesity Locus.
International journal of biological sciences - 1 Jan 2017
Yang Qingyun, Xiao Tiancun, Guo Jiao, Su Zhengquan
Abstract excerpt
In the 21st century, obesity has become a serious problem because of increasing obese patients and numerous metabolic complications. The primary reasons for this situation are environmental and genetic factors. In 2007, FTO (fat mass and obesity associated) was the first gene identified through a genome-wide association study (GWAS) associated with obesity in humans. Subsequently, a cluster of single nucleotide...
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