Article
Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer.
Cancer letters - 1 Nov 2009
Kang Chung-Jan, Chen Yin-Ju, Liao Chun-Ta, Wang Hung-Ming, Chang Joseph T, Lin Chien-Yu, Lee Li-Yu, Wang Tzu-Hao, Yen Tzu-Chen, Shen Chia-Rui, Chen I-How, Chiu Ching-Chi, Cheng Ann-Joy
Abstract excerpt
The aim of this study was to clarify relevant alterations of gene expression associated with the invasive phenotype of oral cancer. To reduce heterogeneity and to obtain data on genes specifically involved in invasive mechanism, we established a highly invasive ORC subline through in vitro Matrigel invasion method. Affymetrix microarrays were used for transcriptome profiling between parental and the highly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.