Article
CD28 proximal promoter polymorphisms in systemic lupus erythematosus susceptibility.
Rheumatology international - 1 Jul 2012
Brambila-Tapia Aniel Jessica Leticia, Dávalos-Rodríguez Ingrid P, Gámez-Nava Jorge Iván, González-López Laura, Medina-Díaz Julio, Bernard-Medina Ana Guilaisne, Salazar-Páramo Mario
Abstract excerpt
CD28 expression and serum levels are significantly increased in patients with SLE than in healthy controls (HC). Until now, there are no studies of proximal promoter polymorphisms of CD28 gene in SLE. Therefore, our objective was to investigate the polymorphisms present in the proximal promoter of CD28 in a group of SLE and HC and to associate the polymorphisms present with the CD28 serum levels of 40 patients...
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