Article
CD8+CD28-, suppressive T cells in systemic lupus erythematosus.
Lupus - 1 Jul 2008
Tulunay A, Yavuz S, Direskeneli H, Eksioglu-Demiralp E
Abstract excerpt
Recent studies show that a CD8+CD28- phenotype of T-cell population inhibits the reactivity of T-helper cells either by a contact-dependent mechanism or with secreting suppressive cytokines. In this study, we have explored the peripheral blood CD8+CD28- T-cell population in 53 patients with systemic lupus erythematosus (SLE) in comparison to healthy and diseased control groups. The distribution of CD28- cells...
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