Article
Polymorphisms of the CTLA-4 exon 1 and promoter gene in systemic lupus erythematosus.
Lupus - 1 Jan 2001
Lee Y H, Kim Y R, Ji J D, Sohn J, Song G G
Abstract excerpt
The objective of this study was to determine whether the polymorphisms of the CTLA-4 exon 1 (+49) and promoter (-318) are associated with susceptibility to systemic lupus erythematosus (SLE) and its clinical features. Polymerase chain reaction of genomic DNA-restriction fragment length polymorphism was used to determine genotypes of the CTLA-4 exon 1 (+49) and promoter (-318) in 80 SLE patients and 86 healthy...
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