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Article

Association of CD28 and CTLA4 haplotypes with susceptibility to primary Sjögren's syndrome in Mexican population.

Journal of clinical laboratory analysis - 1 Jan 2019

López-Villalobos Erika Fabiola, Carrillo-Ballesteros Francisco Josué, Muñoz-Valle José Francisco, Palafox-Sánchez Claudia Azucena, Valle Yeminia, Orozco-Barocio Gerardo, Oregon-Romero Edith

Abstract excerpt

BACKGROUND: Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by destruction of exocrine glands as a result of T and B cells infiltrated in glandular tissue. CD28 and CTLA-4 play a crucial role in T cell activation and inhibition. The aim of this study was to associate CD28 and CTLA4 haplotypes with susceptibility to pSS in patients from western Mexico. METHODS: Polymerase chain reaction and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29992636
DOI: 10.1002/jcla.22620
PMCID: PMC6430371

Genes

CTLA4
CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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