Article
CTLA-4 gene polymorphism in promoter and exon-1 regions in Chinese patients with systemic lupus erythematosus.
Lupus - 1 Jan 2001
Liu M F, Wang C R, Lin L C, Wu C R
Abstract excerpt
Cytotoxic T lymphocyte associated antigen 4 (CTLA-4), a structural homologue of CD28, has been reported to be an important negative regulator of autoimmune diseases. Recent studies showed that CTLA-4 gene polymorphism was associated with several kinds of human autoimmune diseases, suggesting that CTLA-4 gene is probably a general susceptibility gene to autoimmune disease. The present study was conducted in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
