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Article

Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage.

International journal of obesity (2005) - 1 Feb 2012

Musa C V, Mancini A, Alfieri A, Labruna G, Valerio G, Franzese A, Pasanisi F, Licenziati M R, Sacchetti L, Buono P

Abstract excerpt

OBJECTIVE: The objective of the study was to look for uncoupling protein 3 (UCP3) gene variants in early-onset severe childhood obesity and to determine their effect on long-chain fatty acid oxidation and triglyceride storage. METHODS AND RESULTS: We identified four novel mutations in the UCP3 gene (V56M, A111V, V192I and Q252X) in 200 children with severe, early-onset obesity (body mass index-standard deviation...

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Identifiers

PMID: 21544083
DOI: 10.1038/ijo.2011.81
PMCID: PMC3279655

Genes

UCP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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