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Article

Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2001

Halsall D J, Luan J, Saker P, Huxtable S, Farooqi I S, Keogh J, Wareham N J, O'Rahilly S

Abstract excerpt

OBJECTIVE: To investigate whether genetic variation at the UCP3 locus contributes to human obesity. SUBJECTS: Ninety-one obese children (BMI>4 standard deviations from age related mean) and 419 Caucasian adults from the Isle of Ely Study. DESIGN: Single strand conformation polymorphism (SSCP) analysis was used to scan the coding region of the UCP3 gene in 91 severely obese children. A common polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11319649
DOI: 10.1038/sj.ijo.0801584

Genes

UCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.PMID 11319649Read ↗

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The influence of six polymorphisms of uncoupling protein 3 (UCP3) gene and childhood obesity: a case-control study.Semantic proximity Read ↗

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Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study.Semantic proximity Read ↗

Association between uncoupling protein 3 gene and obesity-related phenotypes in the Québec Family Study.Semantic proximity Read ↗

Meta-analysis reveals the association of common variants in the uncoupling protein (UCP) 1-3 genes with body mass index variability.Semantic proximity Read ↗

Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio.Semantic proximity Read ↗

A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population.Semantic proximity Read ↗

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