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Article

APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 May 2011

Cui Shun, Xiong Fei, Hong Yan, Jung Ji-Ung, Li Xing-Sheng, Liu Jian-Zhong, Yan Riqiang, Mei Lin, Feng Xu, Xiong Wen-Cheng

Abstract excerpt

Alzheimer's disease (AD), one of the most dreaded neurodegenerative disorders, is characterized by cortical and cerebrovascular amyloid β peptide (Aβ) deposits, neurofibrillary tangles, chronic inflammation, and neuronal loss. Increased bone fracture rates and reduced bone density are commonly ob...

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Source

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Identifiers

PMID: 21542009
DOI: 10.1002/jbmr.299
PMCID: PMC3126661

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21542009-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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