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Article

Krüppel‐like Factor 4 activates HBG gene expression in primary erythroid cells

3 May 2011

Abstract excerpt

The SP1/Krüppel-like Factor (SP1/KLF) family of transcription factors plays a role in diverse cellular processes, including proliferation, differentiation and control of gene transcription. The discovery of KLF1 (EKLF), a key regulator of HBB (β-globin) gene expression, expanded our understanding of the role of KLFs in erythropoiesis. In this study, we investigated a mechanism of HBG (γ-globin) regulation by...

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PMID: 21539536
DOI: 10.1111/j.1365-2141.2011.08710.x

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