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Article

Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants.

PLoS neglected tropical diseases - 1 Mar 2026

Coelho Sanderson da Silva, Fava Wellington Santos, Burger Eva, Pereira-Latini Ana Carla, Pontillo Alessandra, Venturini James

Abstract excerpt

Paracoccidioidomycosis (PCM) is a systemic fungal infection endemic to Latin America, especially Brazil, where it is considered a neglected occupational disease. Caused by Paracoccidioides spp., PCM presents a wide spectrum of clinical manifestations, ranging from localized to severe disseminated forms. This heterogeneity suggests that host-related factors, including genetic background, may influence disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41855184
DOI: 10.1371/journal.pntd.0014110
PMCID: PMC13001940

Genes

IL10
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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