Article
Interferon-gamma and interleukin-4 single nucleotide gene polymorphisms in Paracoccidioidomycosis.
Cytokine - 1 Dec 2009
Bozzi A, Reis B S, Pereira P P, Pedroso E P, Goes A M
Abstract excerpt
The gene polymorphisms interferon-gamma (IFN-gamma) +874 T/A and interleukin (IL)-4 -590 C/T have been associated with the altered production of cytokines. Therefore, they might be indicative of the occurrence of Paracoccidioidomycosis (PCM) caused by Paracoccidioides brasiliensis. The analysis of single nucleotide polymorphism (SNP) at position+874 IFN-gamma showed an increase occurrence of A/T genotype in both...
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