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Article

Enhanced synaptic plasticity in mice with phosphomimetic mutation of the GluA1 AMPA receptor.

Proceedings of the National Academy of Sciences of the United States of America - 17 May 2011

Makino Yuichi, Johnson Richard C, Yu Yilin, Takamiya Kogo, Huganir Richard L

Abstract excerpt

Phosphorylation of the GluA1 subunit of AMPA receptors has been proposed to regulate receptor trafficking and synaptic transmission and plasticity. However, it remains unclear whether GluA1 phosphorylation is permissive or sufficient for enacting these functional changes. Here we investigate the role of GluA1 phosphorylation at S831 and S845 residues in the hippocampus through the analyses of GluA1 S831D/S845D...

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Identifiers

PMID: 21536866
DOI: 10.1073/pnas.1105261108
PMCID: PMC3100939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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