Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of full length hepatitis C virus particles of 1a genotype through small interference RNA.

Virology journal - 2 May 2011

Ansar Muhammad, Ashfaq Usman Ali, Shahid Imran, Sarwar Muhammad Tahir, Javed Tariq, Rehman Sidra, Hassan Sajida, Riazuddin Sheikh

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV), a member of the Flaviviridae family of viruses, is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Currently, the only treatment available consists of a combination of Pegylated interferon alpha (INF-α) and ribavirin, but only half of the patients treated show a sufficient antiviral response. Thus there is a great need for the development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C

Share to RNA Interference

Share to RNA, Small Interfering

Share to Viral Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 21535893
DOI: 10.1186/1743-422X-8-203
PMCID: PMC3094304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of full length hepatitis C virus particles of 1a genotype through small interference RNA.PMID 21535893Read ↗

siRNAs: Potential therapeutic agents against Hepatitis C VirusSemantic proximity Read ↗

Therapeutic potential of <scp>RNA</scp> interference: a new molecular approach to antiviral treatment for hepatitis <scp>C</scp>Semantic proximity Read ↗

Inhibition of Hepatitis C Virus Infection in Cell Culture by Small Interfering RNAsSemantic proximity Read ↗

Inhibition of hepatitis C virus genotype 3a by siRNAs targeting envelope genes.Semantic proximity Read ↗

Therapeutic application of RNA interference for hepatitis C virus.Semantic proximity Read ↗

Down-regulation of IRES containing 5'UTR of HCV genotype 3a using siRNAs.Semantic proximity Read ↗

Interference of hepatitis C virus RNA replication by short interfering RNAsSemantic proximity Read ↗

Inhibition of expression of hepatitis C virus 1b genotype core and NS4B genes in HepG2 cells using artificial microRNAs.Semantic proximity Read ↗

Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs.Semantic proximity Read ↗

Hepatitis C virus replicons escape RNA interference induced by a short interfering RNA directed against the NS5b coding region.Semantic proximity Read ↗

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells.Semantic proximity Read ↗

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.