Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology

24 May 2007

Abstract excerpt

UNLABELLED: Hepatitis C virus (HCV) replication is highly dependent on host cell factors. Identification of these host factors not only facilitates understanding of the biology of HCV infection but also enables the discovery of novel targets for anti-HCV therapy. To identify host genes important for HCV RNA replication, we screened a library of small interfering RNA (siRNA) that targets approximately 4,000 human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to HIV Research and Treatment
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17518369
DOI: 10.1002/hep.21608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technologyPMID 17518369Read ↗

Integrative Functional Genomics of Hepatitis C Virus Infection Identifies Host Dependencies in Complete Viral Replication CycleSemantic proximity Read ↗

A genome-wide genetic screen for host factors required for hepatitis C virus propagationSemantic proximity Read ↗

Gene Expression Profiling Indicates the Roles of Host Oxidative Stress, Apoptosis, Lipid Metabolism, and Intracellular Transport Genes in the Replication of Hepatitis C VirusSemantic proximity Read ↗

Identification of host cell factors involved in the HCV replication cycleSemantic proximity Read ↗

Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro†‡§Semantic proximity Read ↗

Cellular cofactors affecting hepatitis C virus infection and replicationSemantic proximity Read ↗

Interference of hepatitis C virus RNA replication by short interfering RNAsSemantic proximity Read ↗

Identification and comparative analysis of hepatitis C virus–host cell protein interactionsSemantic proximity Read ↗

Elucidating Novel Hepatitis C Virus–Host Interactions Using Combined Mass Spectrometry and Functional Genomics ApproachesSemantic proximity Read ↗

Regulation of PKR and IRF-1 during hepatitis C virus RNA replicationSemantic proximity Read ↗

Inhibition of Hepatitis C Virus Infection in Cell Culture by Small Interfering RNAsSemantic proximity Read ↗

siRNAs: Potential therapeutic agents against Hepatitis C VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.