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Article

Genetic analysis of the enhancer requirements for polyomavirus DNA replication in mice.

Journal of virology - 1 Feb 1990

Rochford R, Campbell B A, Villarreal L P

Abstract excerpt

In this report, we describe the first systematic analysis of the genetic requirements for polyomavirus (Py) enhancer-activated viral DNA replication during the acute phase of infection in mice. Four mutants were made which substituted XhoI sites for conserved enhancer consensus sequences (adenovirus type 5 E1A, c-fos, simian virus 40, and a glucocorticoidlike consensus sequence). Viral DNA replication in infected...

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Identifiers

PMID: 2153218
DOI: 10.1128/JVI.64.2.476-485.1990
PMCID: PMC249134

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