Article
Genetic analysis of the enhancer requirements for polyomavirus DNA replication in mice.
Journal of virology - 1 Feb 1990
Rochford R, Campbell B A, Villarreal L P
Abstract excerpt
In this report, we describe the first systematic analysis of the genetic requirements for polyomavirus (Py) enhancer-activated viral DNA replication during the acute phase of infection in mice. Four mutants were made which substituted XhoI sites for conserved enhancer consensus sequences (adenovi...
Topics
- Animals
- Base Sequence
- Cell Line
- Chromosome Deletion
- Cloning, Molecular
- DNA Replication
- DNA, Viral
- Enhancer Elements, Genetic
- Genes, Viral
- Genetic Variation
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Oligonucleotide Probes
- Polyomavirus
- Transfection
- Tumor Virus Infections