Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.

Blood - 23 Jun 2011

Afable Manuel G, Wlodarski Marcin, Makishima Hideki, Shaik Mohammed, Sekeres Mikkael A, Tiu Ramon V, Kalaycio Matt, O'Keefe Christine L, Maciejewski Jaroslaw P

Abstract excerpt

In aplastic anemia (AA), contraction of the stem cell pool may result in oligoclonality, while in myelodysplastic syndromes (MDS) a single hematopoietic clone often characterized by chromosomal aberrations expands and outcompetes normal stem cells. We analyzed patients with AA (N = 93) and hypocellular MDS (hMDS, N = 24) using single nucleotide polymorphism arrays (SNP-A) complementing routine cytogenetics. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anemia, Aplastic

Share to Chromosome Aberrations

Share to Cytogenetic Analysis

Share to Karyotyping

Share to Myelodysplastic Syndromes

Share to Oligonucleotide Array Sequence Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 21527527
DOI: 10.1182/blood-2010-11-314393
PMCID: PMC3128479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.PMID 21527527Read ↗

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies.Semantic proximity Read ↗

Single-nucleotide polymorphism array (SNP-A) improves the identification of chromosomal abnormalities by metaphase cytogenetics in myelodysplastic syndrome.Semantic proximity Read ↗

Combining metaphase cytogenetics with single nucleotide polymorphism arrays can improve the diagnostic yield and identify prognosis more precisely in myelodysplastic syndromes.Semantic proximity Read ↗

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.Semantic proximity Read ↗

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML.Semantic proximity Read ↗

Clinical implications of somatic mutations in aplastic anemia and myelodysplastic syndrome in genomic age.Semantic proximity Read ↗

Detection of cryptic chromosomal lesions including acquired segmental uniparental disomy in advanced and low-risk myelodysplastic syndromes.Semantic proximity Read ↗

Clonal Evolution in Aplastic AnemiaSemantic proximity Read ↗

Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes.Semantic proximity Read ↗

Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics.Semantic proximity Read ↗

Genetic characterization of acquired aplastic anemia by targeted sequencingSemantic proximity Read ↗

From cryptic chromosomal lesions to pathologically relevant genes: integration of SNP-array with gene expression profiling in myelodysplastic syndrome with normal karyotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.